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Most of the adverse effects of minoxidil are minor. Flaky skin and moderate burning are typical Minoxidil side effects, as well as minor itching. Additionally, taking minoxidil might make your hair fall out, especially at first. The resting phase of your hair is accelerated with minoxidil, which might cause your hair to come out more often than usual. However, minoxidil also prolongs the hair's development phase. That implies that while some hair loss is normal at first, new hair should come in to replace the hair that has fallen out.