This one is only one step away from FDA approval: https://newatlas.com/disease/obesity/worlds-first-targeted-fat-destroyer What if you could inject a drug into a "problem area" – like abdominal fat – that could kill off fat cells and reduce fat stores in that localized spot? That's what a novel drug from Taiwan's Caliway Pharmaceuticals offers, the world's very first injection that triggers programmed fat-cell death in a targeted area, like the belly or the thighs. Known as CBL-514, this small-molecule drug induces adipocyte apoptosis, which kills fat cells rather than starves them, meaning different regions of subcutaneous fat stores can be rapidly reduced in just a few weeks after a single dose. It's currently being tested for three uses: Non-surgical fat reduction, Dercum's disease – which causes painful fatty tumors to build up around the body, and cellulite. "Administered via subcutaneous injection, CBL-514 has demonstrated a favorable safety and tolerability profile, enabling significant localized fat reduction without surgery and delivering results comparable to liposuction," Caliway has stated.
I remember Lays tired an alternative fat called Olestra back in 1999/2000. If you too much of it, it became a laxative. I remember my British friend ate a whole bag of it (Salt & Vinegar) and he was in & out in the bathroom for like 6 hours or so.